After starting slow, Tennessee cut the lead to two in the fourth quarter before losing its grip on the game.
Tennessee is facing its first true road test of the season. The Vols will try to limit a powerful offense from top-ranked Ole Miss.
After Tennessee's narrow wins over Buffalo and Belmont, they will advance to their first Sweet 16 since 2016.
Tennessee won its first SEC series of the year on Saturday. The Vols look to go for a sweep of South Carolina on Sunday.
True freshman pitcher Chase Burns proved again that no moment is too big. His outing along with four home runs led Tennessee to a commanding win to open SEC play.
Tennessee stayed with its brand so far in 2022 with home runs and dominant pitching, and Tony Vitello became the fastest coach in program history to reach 150 wins.
Tennessee starts their March Madness run on Thursday as they look to be the first-ever Vols' team to make the Final Four.