After starting off slowly, the Vols found a rhythm at the end of the first half and dominated Eastern New Mexico in the second.
Tennessee swept East Tennessee State, Georgia Southern and North Dakota State in the Tennessee Classic this weekend.
No. 5 Tennessee used a Senior Night win over Mississippi State to finish 18-0 at home for the season. The win gives the Vols a chance at a second consecutive SEC regular season title.
Despite just eight points from Grant Williams on Wednesday, No. 1 Tennessee used a versatile attack and suffocating defense to stifle South Carolina for the Vols' 11th consecutive SEC victory.
Maroon 5 performed at Thompson-Boling Arena on Sept. 14 with guests Tove Lo and R City.
Tennessee overcame a 21-point first half deficit to defeat the No. 20 Kentucky Wildcats, 84-77.
With the Lady Vols loss last weekend in the Elite Eight, it meant the end to possibly one of the greatest recruiting classes in Tennessee women's basketball history.